I will reiterate, that the decision is not between 6V and 12V batteries, but the energy value of the batteries versus the cost of the batteries. I've been trying (apparently unsuccessfully) to say this, but maybe I'm saying it too obtusely.
If you're looking at a 225AH 6V battery, the energy value of ONE of those batteries is 1350 watt-hours. You will need two of them to make a 12V system, so in the end you will have 2700 watt-hours.
If you're looking at a 85AH 12V battery, the energy value of ONE of those batteries is 1020 watt-hours. Using two of them still only gets you 2040 watt-hours.
So clearly, if EACH of the batteries costs about the same, two 6V battery is the better option compared to two 12V batteries of those sizes.
But it's not because 6V is better. It's because the batteries you're comparing are not even close to the same energy value.
Another option would be to look at 2V batteries. Of course, it would take 6 of them to make 12V, but heavy duty 2V batteries would be smaller and lighter than high capacity 6V or 12V batteries.
In this case, six 500AH 2V batteries would get you 1000 watt-hours for EACH battery. Putting together a string of 6 would yield 6000 watt-hours. That, and each battery would be a lot smaller and lighter.
So once again, it's not 2V versus 6V versus 12V. It's the watt-hours of the battery per dollar that counts. In the end, it's really more about how much lead is in the battery, and you can (mostly) tell that just by weighing them. The more it weighs, the more energy value the battery will have.
So in the end a 55 lb battery is going to be less energy dense than a 70 lb battery. It's not because it's 2V, or 6V, or 12V. It's because of the energy value of the battery.