We had a 2010 RPod 175 and towed it for about 2 years each with a 2012 Tundra 4.6 and a 2006 Tacoma. Of the 6 travel trailers we've owned the Tundra/Pod combo was probably the best towing combo we've owned, and I've towed with everything from a Chevy S10 to an F250. Since you've owned a Gen 1 Tundra, you obviously know that the 4.7 is a fine engine for light to mid duty towing.
The 4.6 redesign added a 6th speed, a few more horses and ft. lbs. of torque, larger brakes, and a cam chain v/s the 4.7's cam belt. If you're going to stay below about 6000 lbs. of trailer weight, the 4.7 in the 07-09 Tundras, and the 4.6 in the 10 to 13 are just fine for most any towing job. Anything over 5500/6000 lbs, then make sure you get the 5.7. The 5.7 is a great engine, but most people underestimate the 4.6.
We got between 10.5 and 15 mpg towing the Pod with the Tundra--usually 11 to 13. Towing our 5000 lb Kodiak we've dropped to 10 to 12 mpg. Be careful with the Gen 3 Tundra 4.6's, as I've heard that it's difficult to find one with a complete tow package in the 2014 and newer ones, and they've dropped the 4.6 tow rating from my 8200 lbs. to about 6500 lbs. or so--5.7, no problem.
I've towed the S/W area with our Tundra, and pulled your big elevations and darn fast highways with no problems. Towed in S4 (locking out OD 5 and 6) with some drops to S3 on some of your extreme pulls, and never had to worry about holding anybody up. That trip was with the 5000 lb. Kodiak.
Tundra and Pod--fine choice I believe!